This article contributes to an emergent body of research that explores African immigrant women’s experiences in Western destination countries. Foregrounding these immigrant women’s voices in this research, we aim to better understand the challenges they grapple with as newcomers to Canada. Specifically, our study sought to explore the stressors they faced within and outside the family and how these stressors mediate their transition and integration into Canadian society. Three main themes emerged from our study: (1) Participants felt ill prepared to face the challenges of starting life anew in Canada, which included in particular navigating changes in economic wellbeing and gender roles; (2) Participants experienced a lack of community support, which was reflected in both mental/emotional health and parenting issues; and (3) Participants expressed frustration with the manner in which Canadian socio-legal systems manage immigrants’ family issues. Our findings underscore the need to actively engage African immigrant women and men in the development of policies and practices that mediate their everyday lives in Canada. Such policies and practices should consider the changing gender relations, cultural knowledge, and informal support channels within African immigrant communities.