The human immunodeficiency virus (HIV) pandemic is a global public health and social justice issue, where HIV continues to disproportionately affect marginalized populations. This study investigated and captured the experiences of immigrants and refugees living with HIV (IRLHIV) using the social determinants of health framework. This study examined the intersecting factors affecting the health and well-being of IRLHIV in Alberta, Canada, prior to and during the COVID-19 pandemic. Concurrent mixed methods were used. Employing an online survey (n = 124) and photovoice methodology (n = 13), the findings underscored the amplification of pre-existing inequities during the COVID-19 pandemic, intensifying the discrimination and stigma faced by IRLHIV due to both their health status and immigration background.